SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '687f5ff30aa153385ed071625c5809ac9baf5a2331cffb98a6cacba6d2da5cf6' 
  AND token = 'rRpj49TtEQ8iDDSAcQ6SaRXLGWxwz8aV6TsVKvfjs60=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}