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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c24b573bfc466a6472b34f4d34b60e80c53f907f84e52d82dc891bc65b17c106' 
  AND token = 'S4EN9TFr55rxa5YNOUcLR0VJqV1OjKdrJK6fqqf16Xc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}