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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6fea09cc8161dd303d08097537b675ef012d20a3844c026b18321059e3c5c6c2' 
  AND token = '8k/8Ydr9g4lqckOv6WTJzEC1p0cOxT20hmNCstKbDbw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}