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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53b6f56d4c10e671bdac8ea9ed7722a598a32a5440d2eabdaa823882c1797beb' 
  AND token = 'oEr8BAAenY/NWAIXgr9QyFbHrm0voR0Lqv2jrh8FlT0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00064

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}