SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0be22e5f49aac165358b50f59f0dd19291d3bdb4e0ed4b4105ec0c72c96c2f08' 
  AND token = 'cT8FPgTvEsKboAnqTbJ7+ZIGHnjqqQU7IiEf6JmPihM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}