SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed6e76d7c5cc527a059d49269c1937a17e138c1f067d6cedabf4995b4659cc93' 
  AND token = 'ZWapYq2QMTJkOpGQNpCeel0CS9bcD60eWWofHZuOFuc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}