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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e0e793dc84fc2275ba8005f808dbd67961a238f842e1c1a3551f16e11232a63' 
  AND token = 'LE4q/bzyz6v5CrrrXXsSDzc3GL0RWUKVYsc+88a4VEQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}