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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '228071c209dc2d0af994005ae0bc818786c69f89317c56bc6f3702fc45b35add' 
  AND token = 'J4ODldrmEGsC27uAnbP1+WIpf7XxKfmc1M5DNZf7BIs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}