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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '449a87d71a4a25cf9d109cb5e83e67486d618d62054b844a2089304641bc84a0' 
  AND token = 'Qe8DQHBx23jqUo1b8XzFKuo4Wb+gBAr9uoh4Jls+C5U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}