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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c54edd76e4d346021d5fb188748718918842ca8a59120e67fce3a52176b5a36' 
  AND token = 'tqetEKIjsEuMmNfCpSeEnShrLE4wmY0UtDyQNzQQVK8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}