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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '62524aa1bd3d51661e485da3f950a50d0591d9b9d8c7948b22014017ab0c6a45' 
  AND token = 'FtH/gSFCMrWjp2jxGW6m7Mai/Q+4epC1dxERDlQ5VMs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}