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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c5263bf0b1a474deaed312c9007c3a383082fb154c7d6912a21f52cf031aa76' 
  AND token = '2ZEqwAxV1D+Y6QDQibII5ZVwj8hU2NxmpbrZe8vYk2c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}