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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '648e7d3d54d2fa322d5761d8b3f9466e14e4ec8228dd1ffa625ec354aaa26aa9' 
  AND token = 'dm9Khych+j6lRwz7NLAbCWKCF4Hsy2/wxmqt2AknfS0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00067

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}