SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e50bb6835a5c684a7230bf451b22f5fc6c37e299808c6d5f6a0ba11890d325e1' 
  AND token = 'qUsceJwEA9PhjzyfrerVYb3VKbeQ46afDailm5PVe2Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00057

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}