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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c1907f1cf6e41feef0e0009858294b57d2008b1cba4daeff10181e4054f620f' 
  AND token = 'fCzW6gcMXWF1bsBnPGDnV0rRgLW4cvujT4MtMVVVIB0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}