SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7db16d46a8ca1355bd7fcb013631e9d7c66d107acce6723d3c6c6477ed6a9715' 
  AND token = 'f6UF1tAebDCBqw//r9SLzqU8wnECrYVYwke27HulCBw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}