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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c520289a33decfb0d3b949c7a41c597ff5b5acf3bb5f675f8f1993360157f821' 
  AND token = 'YoeMWIdlEHb1pvk6MWfTkwnYa28kvjacDYsN20DO8pk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}