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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e400809e6277917db8a77f2e582741287cce4e03bfc95d3fff565e6fc1feb703' 
  AND token = 'ATd2GPXPry1709AHG9SwINTv5xhPrvyLl6Dz0C//N9k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}