SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '993000e7c2d4eb18ac8de1f6dd2eb352fc51fcf88d10df8631d856b965f991af' 
  AND token = 'tTk2iKdGDDwLOGEtVT5aglYmpLdIw1wzdGV5G7uc/C8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}