SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '985ada8582b8d86b95e1749129c090337d4658eb5cb17124b68c7642231086e5' 
  AND token = 'ztv70QPqWixuqkbWZRYb3Hg5zFUyvXmbzBr9bvn6uRY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}