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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e7a324edeb428d04e02d7af111b82a0fc3dd970c8e98b8df9fe1e62d010c3b9' 
  AND token = 'nIGmHrJjviUiE2o1X3w0uFKbmnOpF4GA3le62dfrNIQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}