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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ee6d418ddca00b2e1b24150e2a8e1f2ef706ab3d1d903bc9f6ee14f269cc144' 
  AND token = 'nfAmxnnqIeCTltgpw+VbngP68PWMEZDzmiToMcjdPF4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}