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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b6af7f18d10437bb0656df31eb14d758d75bcc159f9cf7fbd07ce15be97f2f63' 
  AND token = '2X9Z8QIPgMi4qOLfeRk5heiDKPJaUw+pyBmJOLxlDhc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}