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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4243b48139c30b76127e119993110a1abe82ec3c86e4e1cad96ff26edf8f4082' 
  AND token = 'Mu0rmslb4WF2ZlyCqZsbXKdn3YD10pzT14mH+YXVa9k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}