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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a5a1b8db8390cc3318bee45915d1a798e4f97c692f28fff0f64bb4ac68ad80e' 
  AND token = 'J+NjNiV16G+ypfDI5PMeXia4zrCZMr3qtGoGyrDWCWg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}