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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b2b3c526da23b462f657c406a90e2494ed19eae327bfc4a98f2ea7a5014f1101' 
  AND token = '0i+kZdi879v4YjDgTwj+M4PN9HZLyRXcHcdb3SyD6Uk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}