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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3424366cbf5f646f71358dbfb7d686f82b4d508a2580afa5da47eff1560a6380' 
  AND token = 'CPPmKOfJQ5dYAXvBiowZYAl6Cqtf/3t9M0jQf0fmu3I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}