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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1131a8e326b30cf1640308c3792c434a67940a35d229933f2d88307330b1d202' 
  AND token = 'JnRNS/CJJ+jDtS2qRjpXbsXdX45KKkZJIDQ4+D7wYqQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}