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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a373cb54ce6efc633438d54f5acf84dc22d931213c22f15b4dba85231a00f0c3' 
  AND token = 'I7lP7pxzYW+EjeEPHAw3fepFiaRUezLAZzv/dZN53M0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}