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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '39cda5954245d1de6f8227c8990e2905cb95730c5216e56d565b726db49fa004' 
  AND token = 'GyQFx2jgvr8Z5BeGcI7d8WWgGkcKnyvqu42QqBQTmmc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}