SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1b15675131d1de2f11ad263ec06d855162f55109d370d3f9eb4d658f1179029' 
  AND token = 'kU9tfkYC69lW/NBjnjVOAW6dpTTJuFabAiI2zVTA72Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}