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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce51f3eff528906db7d390871574e2ab1f736bd3b7fbf4cbf611dd340d1afb6a' 
  AND token = 'cFxhqdFL/da2nbBs1PvphyrrGvWwquXHdqF6LlMQOuk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}