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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33bf3ce74dc53c8b72c4b6c2419e06916b1820bc305b9a714a358198a09f68a2' 
  AND token = 'ddZ5eaJalh3v1Vsg1jbfSsJj1Tv0HyXXZY7cvDyhXac=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}