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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00e32b7c6b0ff8c375bedae11f762e18fc91859e54b3fbdb606cd448af2c3094' 
  AND token = 'xTIfmV8WED7xTIr3NgkmhVuuYTuIhRO06AzWFRI79tE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}