SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6ca2e39dad7c38f8347549e49cd9a743c45d6391db01080cd65b8d54151dc4f' 
  AND token = 'NeR079zWg2QSaFXumXDNSN7WjBOcws1T4xWVuPKe5oA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}