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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e42e7ac0a37e94355aa2e600f90adb365f7176da0ed0b1e93e9443209372758' 
  AND token = 'gnyMrrtIQJQ8w9lIJGPlYF6HJ8B8yQrupZ9wbMPftOQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}