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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3b964d851b7ebf2c585e88964796910ebf66e248e1fe38d37d10adc308fab38d' 
  AND token = 'rIyQ/gUFC0p+sGUe6MDUMyF5Dhuc4SahEDv5nRDGE4M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}