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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c15c309956705176e7537e0febba06e309bd55605b895c6d3c07fe7d84d993a' 
  AND token = 'LqNY8ZJ2dO8N1EYqnbWzXuSfzySghuSMYnyvnBsnShA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}