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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6b20fbff35173ae49901893cc2b8c454041996f5fb7ef540abfa3d1f2aa52cd' 
  AND token = '25MNIxUgcpAN1+IX5p1CRusy1e1iDqdjxwvAzhksAk0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00079

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}