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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '05122f0bdbff45763d3576fa3dc469a7e310c0d50930034487c0a0fcd3ae9570' 
  AND token = '79GrCWKRlMc/0QTThBB5OPj7sk7STSDTerQnf5qcfCg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}