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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c537c9698be210c9c2ad5c4cd833f26175b1490055a605b3c788ec9e0bf327f6' 
  AND token = 'ZkNVy/2ShrTzbFIFNGGpDrdacZ56OpIgzxDHdt30F3k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}