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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '86f6663f47e193f6ff3f82c1e87d6cb6e9c629a35eae41131d1ed09b8d88713a' 
  AND token = 'KJbEvRx2JrqJlm6i05YKEHTl2KgnnAHgEJ44t9CUXlQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}