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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2ae98d468a0f9a4fbc4cbffc673bd80694c59d3da268292afbb14edb0461eff' 
  AND token = 'yWLHqeScXvlDPX6cb8mVk9+1UECCSSSsvAgnQKIDUxw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}