SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c4ac1c31f8b4ae617234d9403fc8b63e615b0cce1fb1f7b79e21da06a41137a' 
  AND token = '++U+ODAIAclB6eyoQ5D/uKBuQe/wF92DbT2rHOiteD8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}