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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '446099f5d5d4185d0b45e9901fc9b9291781539b1406c0602992c879eb01376d' 
  AND token = 'UpjxRBUnpuHYZJ1JkkzLxAKjBTPX0T0BnPZhWsPCE28=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}