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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3dba33e046afa1185a27d99b7cc58ac535a031574aed9ca7e6740b2c27e0137e' 
  AND token = '1ppEr0TUvEZzuNdjZBonls50nq4FYRPgXLxMywGNjwo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}