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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e7848614555722c6b752500e6133c04a2367737a914ac57d2faa0102434ff32d' 
  AND token = '+1IyYa6On0l+5sClLgWXgg1iR2f/t5Rl9wjEkbUvj3k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}