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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c8a9ac85d1515544972431143a8f996920e74b1f05edb927244d103e99a6d10' 
  AND token = '7kNL8GnPzAPyM/U9IiR58KMqaTNFwkVUN0WGg5zGzdk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}