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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '23b8bf048a230d9dd0b2068555e00f2050dd91b88d691686156d7bc2d93f68c5' 
  AND token = '1Ae5hsHp4UMCN8i37t8+fsx32KS4WDlUhaXKlIvKFzA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}