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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '58cb72ecc6dbde599e90e2e43d392f0747a4fb9a00a7fc181d223c53a48ab6f1' 
  AND token = 'UWQiP4oIqD8fCY/5QZyPv84XOfGqDHDm3gFXSL2/HUU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}